It was as an undergraduate at Cambridge where Dr Harriet Groom's passion for molecular virology first began. Harriet completed her PhD under the supervision of Andrew Lever in the Department of Medicine, understanding the control of HIV gene expression. She then moved to the National Institute of Medical Research (now Francis Crick Institute) in London where she helped to disprove the reported novel retrovirus XMRV’s link to human infection and disease. Harriet then began my work on cellular inhibition of retroviruses, focusing on HIV, before moving back to Cambridge in 2015 as a Henslow Research Fellow at Downing College and an Associate Principal Investigator in the Department of Medicine where she continued work on cellular inhibitors of HIV. In her current fellowship Harriet continues to unpick how the intricate interactions between cells and viruses during infection can dictate host response and help us understand normal cell behaviour using retroviruses, herpesviruses and coronaviruses as model systems.
Harriet is currently a Stanley Elmore Research Fellow at Sidney Sussex College and an associated PI in the Department of Medicine, where she researches the molecular interactions between retroviruses and human cells.
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Volcanoes are hazardous and beautiful manifestations of the dynamic processes that have shaped our planet. Volcanoes impact our environment in numerous ways. Over geological time volcanic activity has resurfaced the Earth and provided life with a terrestrial substrate upon which to proliferate. Volcanic degassing has shaped our secondary atmosphere and as part of the process of plate tectonics, maintained just the right amount of water and carbon dioxide at the surface to produce a stable and equitable climate. Magma in the subsurface in volcanic environments today gives Society geothermal energy. The fluids degassed from magmas in the plumbing systems of volcanoes give rise to hydrothermal ore deposits, the source of much of our copper and other metals, critical to the energy transition. In this lecture I will describe the nature and importance of magma degassing for our atmosphere and oceans, as a source of both pollutants and nutrients, and in the formation of mineral deposits. I will describe my own research in carrying out measurements of volcanic gases (using a range of spectroscopic methods, from the ground and using drones), and analysis of erupted lavas, to understand the chemistry and physics of volcanic outgassing and its role in sustaining our planetary environment.
One of the many outstanding achievements of G I Taylor was the discovery of relatively simple statistical laws that apply to highly complex turbulent flows. The emergence of simple laws from complexity is well known in other branches of physics, for example the emergence of the laws of heat conduction from molecular dynamics. Complexity can also arise at large scales, and the structural vibration of an aircraft or a car can be a surprisingly difficult phenomenon to analyse, partly because millions of degrees of freedom may be involved, and partly because the vibration can be extremely sensitive to small changes or imperfections in the system. In this talk it is shown that the prediction of vibration levels can be much simplified by the derivation and exploitation of emergent laws, analogous to some extent to the heat conduction equations, but with an added statistical aspect, as in turbulent flow. The emergent laws are discussed and their application to the design of aerospace, marine, and automotive structures is described. As an aside it will be shown that the same emergent theory can be applied to a range of problems involving electromagnetic fields.
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