Department of Engineering and Newnham College, University of Cambridge.
Research interests in materials engineering and sustainability.
Professor of Materials Science, Department of Materials Science & Metallurgy, University of Cambridge
Professor of Observational Cosmology and Astrophysics, Institute of Astronomy, University of Cambridge
Professor in Theoretical and Mathematical Physics, DAMTP, University of Cambridge
Department of Pure Maths and Mathematical Statistics and First Bursar, King's College Cambridge
Professor of Mathematical Physics, Department of Applied Mathematics and Theoretical Physics, Clare College, University of Cambridge
Senior Lecturer, Department of Physiology Development and Neuroscience, University of Cambridge
Professor of Image and Signal Processing, Department of Engineering, University of Cambridge.
Senior Lecturer and Curator, University Museum of Zoology, University of Cambridge
Plant Virology & Molecular Plant Pathology Group, Department of Plant Sciences
Professor of Physical Chemistry
Professor of Molecular Modelling, Engineering Laboratory, University of Cambridge.
Department of Physics The Cavendish Laboratory, University of Cambridge
Professor Emeritus Dept of Physiology, Development and Neuroscience Clare College, University of Cambridge
Research interests in the development of the nervous system.
Professor of History of Science and Medicine, Department of History and Philosophy of Science, University of Cambridge
Associate Professor in Palaeobiology, Department of Earth Sciences, University of Cambridge
Department of Materials Science and Metallurgy, University of Cambridge
Deputy Head of School, Faculty of Science and Engineering, Anglia Ruskin University
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Finding and understanding the nature of the first stars at cosmic dawn is one of the most important and most ambitious goals for modern astrophysics. The first populations of stars produced the first chemical elements heavier than helium and formed the first, small protogalaxies, which then evolved, across the cosmic epoch, into the large and mature galaxies, such as the Milky Way and those in our local neighbour. Equally important and equally challenging is the search, in the early Universe, of the seeds of the first population of black holes, which later evolved in the supermassive black holes at the centre of galaxies, with masses even exceeding a billion times the mass of the Sun. When matter accretes on such supermassive black holes it can become so luminous to vastly outshine the light emitted by all stars in their host galaxy.Since its launch, about two years ago, the James Webb Space Telescope has been revolutionizing this area of research. Its sensitivity in detecting infrared light from the remotest parts of the Universe is orders of magnitude higher than any previous observatory, an historical leap in astronomy and, more broadly, in science. I will presents some of the first, extraordinary discoveries from the Webb telescope, which have resulted in several unexpected findings. I will also discuss the new puzzles and areas of investigation that have been opened by Webb’s observations, how these challenge theoretical models, and the prospects of further progress in the coming years.
The maintenance of oxygen homeostasis is a key physiological challenge, inadequate oxygen (hypoxia) being a major component of most human diseases. The lecture will trace insights into human oxygen homeostasis from the founding work of William Harvey on the circulation of the blood to the molecular elucidation of a system of oxygen sensing that functions to measure oxygen levels in cells and control adaptive responses to hypoxia. The lecture will outline how the oxygen sensitive signal is generated by a set of ‘oxygen splitting’ enzymes that modify a transcription factor (HIF) to signal for its degradation (and hence inactivation). It will attempt to illustrate and rationalise the unexpected in biological discovery and discuss the interface of discovery science with the development of medical therapeutics.
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